Optimalisering og validering av en prognostisk tarmmikrobiota-test for pasienter med ulcerøs kolitt

Offentlig prosjektsammendrag

Ulcerative colitis (UC) is a chronic inflammatory bowel disease, and currently, there is no non-invasive method available to predict whether a patient will experience mild or severe disease course. Choosing the right treatment strategy for each patient remains a medical challenge. The gut microbiota plays a crucial role in this context, as the balance between bacterial species has been shown to influence disease activity. Mapping the composition of the gut microbiota can therefore offer valuable insights into the mechanisms driving disease progression in UC. Genetic Analysis AS will develop an easy-to-use, in vitro diagnostic test to predict disease course and the likelihood of treatment escalation in UC patients. By analyzing the gut bacterial profile, the test will deliver actionable results to help clinicians make informed decisions about disease management and therapeutic strategies.