SF-MarBioTech

Offentlig prosjektsammendrag

Organisms in the marine environment represent a largely unexploited source of highly valuable biomolecules. Due to the development of sequencing technologies in the last few decades, we are now able access a vast amount of sequence information of metagenomes of cultivable and non-cultivable marine organisms. Unfortunately, our abilities to link such sequence information with function lags completely behind. It is virtually impossible to identify novel proteins and enzymes based on sequence based screenings, only. Therefore, the goals of MarBioTech are to develop innovative tools and technologies to advance function-based searches in combination with sequence-based searches and to deliver valuable enzymes of marine origin. The target enzymes in this project will exhibit novel highly active RNA polymerases as well as DNA nucleases for metagenome mining and molecular biology.