SpinChip Digital Development

Offentlig prosjektsammendrag

Project idea: "Enable scalability in number of robust high-quality assays to be developed for SpinChip's diagnostics platform by combining microfluidic simulations, advanced computer vision and state-of-the-art machine learning." SpinChip Diagnostics is developing a game changing, high sensitivity, analysis platform for point-of-care in vitro diagnostics based on their proprietary dual axel centrifugal technology. The innovation potential of the platform is in its flexibility and its effective microfluidic processing of different invitro diagnostic assays. This project is of essence to realize the value creation potential, by improving the process of developing new assays for the SpinChip platform. The project will combine microfluidic simulation of the assays and recent developments within advanced computer vision and state-of-the-art machine learning. A general framework to enable scalability and effectiveness in the development of new assays and its vision based fail safes, will be established. The project will lead to: - reduced time to market for each new assay - improved performance (assay processing time and repeatability of analysis) - improved reliability as obtained by advanced real-time fault detection SpinChip has already designed, developed and tested their generic platform by running and analysing biochemical assays. Two assays based on totally different assaying principles are demonstrated: 1. Cardiac Troponin I (cTnI), detection range 5ng/L to 10µg/L, in < 15 minutes using 15µL blood. 2. C-reactive protein (CRP), detection range 0.5mg/L to 150mg/L, in < 2 minutes using 10µL blood. Image data from these assays will be used for creating the test and training image data needed in the project.